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D1–D2 dopamine receptor heteromer : ウィキペディア英語版 | D1–D2 dopamine receptor heteromer
The D1–D2 dopamine receptor heteromer is a receptor heteromer consisting of D1 and D2 protomers. == Structure == D1 and D2 receptors interact primarily through discrete amino acids in the cytoplasmic regions of each receptor, with no involvement of transmembrane parts. The intracellular loop 3 of the D2 receptor contains two adjacent arginine residues, while the carboxyl tail of the D1 receptor possesses two adjacent glutamic acid residues. The two receptors can form a heteromer complex via a salt bridge between the guanidine moiety and the carboxylic group.
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